Substantiation of chen-chiu therapy use under disordered reparative regeneration of leg bones to prevent pseudoarthrosis formation

Цяо Г., Сидорова Г.В., Верхозина Т.К., Тишков Н.В., Лепехова С.А., Гольдберг О.А., Цяо Л., Чжай Ц., Лю Ц., Чжан Ю., Тонг С., Диао Л.

Abstract


Purpose. To study the possibility of stimulating bone tissue reparative regeneration by chen-chiu therapy technique for disordered posttraumatic regeneration of leg bones.
Materials and Methods. 24 Chinchilla male rabbits of 3-kg weight at the age of 6 months used in the studies. We modeled pseudoarthrosis in all the animals by performing osteoclasia of both leg bones, and after that an external fixator was applied. Then we created the conditions which prevented normal process of reparative regeneration. The animals were divided into two groups (a control group and an experimental one). Chen-chiu therapy used in the animals of experimental group and influenced their biologically active points.
Results. The obtained data of histology and radiography evidence of the fact that despite the conditions of disordered bone reparative regeneration in all the animals of experimental group subjected to chen-chiu therapy fracture consolidation observed in 100% of cases by the completion of experimental study, i.e. on Day 50, while in the animals of control group union didn’t occur in bone defect area and pseudoarthrosis formed in the zone of fracture.
Conclusion. As it has been demonstrated by animal studies, the conditions of disordered reparative regeneration with delayed juxtaposition of fragmental ends on Day 14 lead to pseudoarthrosis formation, while the use of chen-chiu therapy techniques in the early postoperative period allows to prevent pseudoarthrosis formation with fracture healing and callus forming.

Keywords


disordered reparative bone regeneration, chen-chiu therapy, an external fixator

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