Osteogenesis imperfecta: the role and place of orthopedic surgery of the lower extremities

Popkov D.A., Mingazov E.R., Gubin A.V., Gvozdev N.S., Aranovich A.M., Semyonov A.L.


Surgical correction of orthopedic problems in children and adults with severe osteogenesis imperfecta is of interest to the medical community.
The aim of this study was to review the current relevant literature on the role of orthopedic surgery in the treatment of children and adults with osteogenesis imperfecta and the integration of surgery into a multidisciplinary approach to the treatment of patients with osteogenesis imperfecta. The review is based on the material of the report presented at the first educational conference of the European Pediatric Orthopedic Society which was held in Russia at the Ilizarov Center in 2021.
Material and methods
To prepare the review, we searched for information sources at the scientific platforms such as PubMed, Scopus, ResearchGate, RSCI, as well as published products (Elsevier, Springer).
Results and discussion
The review includes a discussion of the classification, indications, features of the surgical technique and the early postoperative period, the role of early functional loading, the features of long-term treatment results of using telescopic transphyseal constructs in the correction of deformities of lower limb long bones as well as issues of the combination of orthopedic surgery and bisphosphonate therapy.
Orthopedic support of children and adults with severe and moderate types of osteogenesis imperfecta requires construction of a multifactorial strategy that takes into account the requirements of physical therapy and medication treatment, as well as the use of specialized implants, instrumentation and methods of surgical intervention, while an optimal solution has been still sought.


osteogenesis imperfecta, deformity correction, telescopic nail

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DOI: http://dx.doi.org/10.18019/1028-4427-2021-27-4-461-467


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