Roentgen-and-morphological characteristics of shaft tibial fracture consolidation under intramedullary osteosynthesis using wires with hydroxyapatite coating

Попков А.В., Попков Д.А., Дьячков К.А., Осипова Е.В., Тведохлебов С.И., Больбасов Е.Н.

Abstract


Purpose. Quantitative evaluation of the roentgen-and-morphological characteristics of long bone shaft fracture healing experimentally.
Material and Methods. Open tibial fracture modeled in dogs experimentally, osteosynthesis using the Ilizarov fixator performed with hydroxyapatite-coated wire intramedullary insertion. A quantitative analysis of fracture consolidation dynamics made using computed tomography methods, and digitized images of X-rays made in two standard views investigated using “DiaMorph” hardware-and-software complex.
Results. Fracture consolidation clinically and by X-rays occurred after 3-4 weeks. The density of regenerated bone in the intermediate zone three weeks after osteosynthesis amounted to 37% of the density of contralateral limb cortex, and besides the share of highly mineralized structures in the medullary space increased significantly (р=0.003) more than 5-fold, and that in the zone of cortical plate – 3-fold.
Conclusion. The results of the study evidence of a positive effect of intramedullary wires with hydroxyapatite coating on the course and intensity of reparative osteogenesis during the fracture healing and the onset of consolidation within a month. The data allow to recommend this comparatively little-invasive technique of osteoreparation condition optimization for using in complex with other methods of conservative and surgical treatment of bone fractures.

Keywords


transosseous osteosynthesis, intramedullary wires, hydroxyapatite coating, fracture consolidation

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